Clinical Characteristics of Metastatic Gastric Tumors: A Report of 8 Cases in a Single Hospital

Metastatic gastric tumors (MGTs) mean the tumor cells that attack the stomach and grow there through blood vessel, lymph vessel, and other pathway, consistent with the primary tumor in phenotype, which are clinically uncommon, and information on MGTs is generallylimited to single case reports. Here we present a clinical series of 8 cases with MGTs, in attention to discuss the clinical characteristics,diagnosis and treatment, and prognosis of MGTs. Our data showed that MGTs are rare, with a male predominance, and the cause ofdeath was multiple organ metastases in most cases. Heterochromous MGTs showed a significantly better prognosis than simultaneousMGTs, and a long interval between initial radical excision of the primary tumor and appearance of gastric metastasis was found to beassociated with good prognosis.




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Juvenile Ossifying Fibroma - WHO Type

Juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate mean that it is important to make an early diagnosis, apply the appropriate treatment and, especially, follow the patient up over the long term. In the current article we report a case of juvenile ossifying fibroma-WHO type in 12yr old patient which was clinical and histopathologically challenging as it was asymptomatic and at an unusual location.


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Prostate Cancer – Double Vision but Solitary Lesion

A 53 year old man with a background of castrate-sensitive prostate cancer on intermittent androgen deprivation therapy (ADT) presented with right sixth nerve palsy secondary to a solitary right petroclival lesion involving adjacent dura and bone. The clinical and imaging characteristics of the lesion were consistent with a number of differential diagnoses (including metastatic prostate cancer, meningioma and chondrosarcoma). The patient initially declined biopsy and ADT was recommenced but the lesion continued to enlarge despite an excellent biochemical response. A subsequent biopsy of the petroclival mass demonstrated a WHO grade I meningioma and the patient proceeded to have definitive stereotactic radiotherapy. 

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Ascending Aortic B-Cell Lymphoma Masquerading as Intramural Hematoma: A Case Report

We report the case of a 74 year old female who presented with imaging concerning for an intramural hematoma of the ascending aorta. Despite multiple imaging modalities consistent with intramural hematoma, operative findings confirmed a peri-aortic lymphoma or what was once lymphoma.
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Olfactory Neuroblastoma (Esthesioneuroblastoma) following Retro-Orbital Irradiation for Graves’ Ophthalmopathy

Malignancies of the nasal cavity are uncommon and comprise less than 1% of all malignancies. While almost half of the sinonasal cancers are squamous cell carcinomas, olfactory neuroblastoma, also known as esthesioneuroblastoma, comprise less than 6% of nasal malignancies. After the initial description in 1924 by Berger and Luc, less than 1,000 cases were reported until 1997. These are tumours of neuroectodermal origin which are thought to arise from the olfactory epithelium in the nasal cavity. The mean age at presentation is 53 years, with most cases occurring in patients between 40 and 70 years of age. Although there is a male predominance, no other risk factor is commonly associated with this disease. 
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Hepatic Angiosarcoma, going but not gone. Lessons from a single centre experience

Hepatic angiosarcoma is a rare tumour that is often difficult to diagnose. Historically, most cases of hepatic angiosarcoma were seen in the setting of industrial epidemics caused by exposure of workers to toxins such as vinyl chloride. Cases associated with recognised exposure to carcinogens have fortunately been extremely rare for the last three or more decades. However, the tumour has by no means disappeared in the Australian community. In this case series, we describe three cases of hepatic angiosarcoma that were seen at our institution since 2002. The first case presented with cholestatic liver function tests and was found to have angiosarcoma on liver biopsy. In the second case, the patient was admitted for decompensated liver disease on a background of presumed hepatitis B cirrhosis. The diagnosis of hepatic angiosarcoma was made only at autopsy after the patient died from multi-organ failure.


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Thrombotic Microangiopathy Associated with Intravenous Injection Of Opana Er®: University Medical Center Case Series.

In response to the rapidly rising intravenous opioid abuse epidemic, the United States Food and Drug Administration is currently promoting the development of prescription opioid tablets that are specifically formulated to deter abuse. Opana ER®; (Endo Pharmaceuticals) recently underwent reformulation to include a crush-resistant coating. Only recently described, illicit intravenous injection of reformulated Opana ER®; is associated with a distinctive clinical syndrome of thrombotic microangiopathy. Ten patients with the appropriate history and presenting symptoms were identified within an 8 month interval (July 2012 through February 2013) at the University of Tennessee Medical Center (UTMC) Knoxville with ICD-9 code of 446.6 (thrombotic microangiopathy) by electronic search. Review of laboratory data, electronic medical records, blood product usage, and total hospital admission charges were compiled for these individual patients.





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