Background: This study investigated comparative concentrations of individual amino acids, total amino acids (TAA), non-essential amino acids (NEA) and essential amino acids (EAA) in the blood after the administration of Rice Protein Isolate (RPI) compared to Whey Protein Isolate (WPI).
Methods: After a 12 hour overnight fast, 10 trained male subjects were randomly assigned to receive either 48 grams of RPI or WPI in a double-blind, crossover design, separated by a washout period of 7 days. Blood draws were taken immediately prior to and at 1, 2, 3, and 4 hours following consumption of WPI or RPI. Pharmacokinetic parameters of plasma concentrations of amino acids were analyzed by a repeated measure ANOVA. AUC0-t, and Cmax were analyzed by t-tests.
Results: WPI and RPI showed a significant difference between Tmax for essential amino acids (EAA: RPI 87 ± 7 min, WPI 67 ± 4 min, p=0.03), non-essential amino acids (NEA: RPI 97 ± 4 min, WPI 71 ± 5 min, p<0.001), and total amino acids (TA: RPI 93 ± 4 min, WPI 69 ± 3 min, p<0.001), however no significant differences were detected for AUC (EAA: RPI 649.5 ± 140.9 nmol/ml, WPI 754.2 ± 170.0 nmol/ml, p=0.64; NEA: RPI 592.7 ± 118.2 nmol/ml, WPI 592.7 ± 121.2 nmol/ml, p=0.98; TAA: RPI 615.9 ± 88.6 nmol/ml, WPI 661.1 ± 98.7 nmol/ml, p=0.74), and neither for Cmax (EAA: RPI 176.1 ± 37.5 nmol/ml, WPI 229.5 ± 51.2 nmol/ml, p=0.41; NEA: RPI 160.0 ± 31.1 nmol/ml, WPI 178.4 ± 34.0 nmol/ml, p=0.69; TA: RPI 166.6 ± 23.4 nmol/ml, WPI 199.3 ± 28.8 nmol/ml, p=0.38). On an individual amino acid basis, WPI was faster or equal for all amino acids with the excpetion of leucine, which reached Cmax faster in the RPI group.
View Journal of Nutrition and Health Sciences (JNH)
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